Cardiovascular Health – Blood Pressure S

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only A through D-quality evidence.

Screen Shot 2020-06-03 at 11.30.07 AM.pn

Disclaimer

The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

Cardiovascular Health – Blood Pressure Support

Magnesium

300-450mg of elemental magnesium, total per day, 1 to 6 months1,2

Consistent supplementation resulted in a decrease of both systolic and diastolic blood pressure1,2
An inverse correlation between levels of circulating magnesium and the incidence of hypertension has been clearly identified3,4

Magnesium in the Fullscript catalog.

L-arginine

2.4g, total per day, minimum 6 months5

Reduction in blood pressure observed in patients with mild to moderate hypertension5
Compared to placebo, L-arginine supplementation was shown to lower systolic blood pressure in patients with gestational hypertension6

L-Arginine in the Fullscript catalog.

Garlic (Allium Sativum)

300 to 960mg, total per day, minimum 8 to 12 weeks7,8,9

Consistent supplementation for 8-12 weeks has demonstrated reduction in both systolic and diastolic blood pressure7,8,9,10,11
Garlic supplementation is widely considered a safe and effective approach to hypertension7,8,10,11

Garlic (Allium Sativum) in the Fullscript catalog.

References

https://www.ncbi.nlm.nih.gov/pubmed/28724644

https://www.ncbi.nlm.nih.gov/pubmed/27402922

https://www.ncbi.nlm.nih.gov/pubmed/28476161

https://www.ncbi.nlm.nih.gov/pubmed/28927411

https://www.ncbi.nlm.nih.gov/pubmed/27817128

https://www.ncbi.nlm.nih.gov/pubmed/23435582

https://www.ncbi.nlm.nih.gov/pubmed/23404465?dopt=Abstract

https://www.ncbi.nlm.nih.gov/pubmed/20594781?dopt=Abstract

https://www.ncbi.nlm.nih.gov/pubmed/19390538?dopt=Abstract

https://www.ncbi.nlm.nih.gov/pubmed/26764326

https://www.ncbi.nlm.nih.gov/pubmed/25837272

Cardiovascular Health – Cholesterol Support

Red Yeast Rice (Monascus purpureus)

1200-2400mg, once per day, minimum 8 to 12 weeks1

Decrease in LDL, total cholesterol and homocysteine1,2,3
10 mg of Monacolins K (constituent of Red Yeast Rice) was shown to decrease LDL-C2
Red Yeast Rice has been shown to be as effective as simvastatin for its capacity to lower lipids4

Red Yeast Rice in the Fullscript catalog.

Coenzyme Q10 (CoQ10)

200mg, once per day, minimum 3 months5

CoQ10 has been shown to reduce total cholesterol and LDL, and increase HDL5,6
Reduction in triglyceride levels observed with consistent supplementation7

Coenzyme Q10 (CoQ10) in the Fullscript catalog.

Omega 3 Fatty Acids

2.52g, total per day, minimum 3 months8

By reducing VLDL, both EPA and DHA when administered independently resulted in reduced fasting circulating triglyceride levels9
DHA has shown to have a greater impact in decreasing triglycerides and increasing HDL10

Omega 3 Fatty Acids in the Fullscript catalog.

Garlic (Allium sativum)

400-600mg, once per day, minimum 12 weeks11,12

Decrease in LDL (low density lipoprotein) and total cholesterol was observed 13,14,15
Increase in HDL (high density lipoprotein) in addition to a decrease in alipoprotein B and an increase in the LDL/alipoprotein B ratio was observed16

Garlic (Allium sativum) in the Fullscript catalog.