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Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only A through D-quality evidence.

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Disclaimer

The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

Men’s Health – Sexual Health

Korean ginseng (Panax ginseng)

2000mg, total per day, minimum 8 weeks3,4,5

  • Panax ginseng was shown to be effective for the treatment of erectile dysfunction1

  • IIEF score, sexual desire, frequency of intercourse, degree of sexual desire, erection, rigidity, penetration and maintenance of erection was all significantly improved2,3,4,5

Panax ginseng in the Fullscript catalog.

Tribulus (Tribulus terrestris)

750mg, total per day, minimum 3 months6,8

  • Improvement in intercourse satisfaction, orgasmic function, sexual desire, overall satisfaction and GEQ response was observed in patients with mild to moderate erectile dysfunction6,7

  • Increase in total testosterone and IIEF was observed6,8

Tribulus terrestris in the Fullscript catalog.

Maca (Lepidium meyenii)  

1500-2400mg, total per day, minimum 8 weeks9,11

  • Significant improvement in physical, psychological, and social performance-related SAT-P score9

  • Greater increase in IIEF score compared to placebo9

  • Improved sexual desire was observed and seem to be an independent effect of Maca10,11

Lepidium meyenii in the Fullscript catalog.

References 

1

A

https://www.ncbi.nlm.nih.gov/pubmed/18754850

2

B

https://synapse.koreamed.org/search.php?where=aview&id=10.4111/kju.2009.50.2.159&code=0020KJU&vmode=PUBREADER

3

B

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735289/

4

B

https://www.ncbi.nlm.nih.gov/pubmed/16855773

5

C

https://www.ncbi.nlm.nih.gov/pubmed/12394711

6

B

https://www.ncbi.nlm.nih.gov/pubmed/28364864

7

B

https://www.ncbi.nlm.nih.gov/pubmed/23723641

8

B

https://www.ncbi.nlm.nih.gov/pubmed/30253697

9

B

https://www.ncbi.nlm.nih.gov/pubmed/19260845

10

C

https://www.ncbi.nlm.nih.gov/pubmed/19781622

11

C

https://www.ncbi.nlm.nih.gov/pubmed/12472620

Men’s Health- Prostate Care

Saw Palmetto (Serenoa repens)

320-960mg, total per day, minimum 3 to 5.5 months1,2

  • Decrease in inflammatory markers that contribute to the evolution of chronic prostatic inflammation and subsequent hyperplasia1

  • Saw Palmetto supplementation resulted in an increase in average flow rate values, and decreases in prostate volume and IPSS score3

Saw Palmetto (Serenoa repens) in the Fullscript catalog.

Lycopene

15mg, total per day, minimum 6 months4

  • Reduction in PSA levels and overall improvement of IPSS score5

  • Consistent lycopene supplementation has been shown to inhibit the overall progression of BPH5

Lycopene in the Fullscript catalog.

Beta-sitosterol

130mg, total per day, minimum 6 months6

  • Beta-sitosterol has been shown to improve IPSS score8

  • Overall improvement of quality of life (QOL), urinary and flow scores, which include maximum urinary flow and postvoid residual urine volume7,8

Beta-sitosterol in the Fullscript catalog.

Pygeum (Pygeum africanum)

100mg, total per day, minimum 2 months11

  • IPPS score and QOL were improved by 38% and 35% respectively11

  • A decrease of 19% in nocturia, 24% in residual urine volume and an increase of 23% in peak urine flow was observed10

  • Urologic symptoms and flow measures were improved9,10

Pygeum africanum in the Fullscript catalog.

References 

1

C

https://www.ncbi.nlm.nih.gov/pubmed/26891611

2

B

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049653/

3

B

https://www.ncbi.nlm.nih.gov/pubmed/28991765

4

C

https://www.ncbi.nlm.nih.gov/pubmed/18156403

5

A

https://www.ncbi.nlm.nih.gov/pubmed/28440323

6

B

https://www.ncbi.nlm.nih.gov/pubmed/9313662

7

A

https://www.ncbi.nlm.nih.gov/pubmed/10368239

8

B

https://www.ncbi.nlm.nih.gov/pubmed/10792163

9

A

https://www.ncbi.nlm.nih.gov/pubmed/11099686

10

A

https://www.ncbi.nlm.nih.gov/pubmed/11869585

11

B

https://www.ncbi.nlm.nih.gov/pubmed/10475357

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